Congenital insensitivity to pain is the syndrome of not feeling pain. See what it is and what its symptoms are.

The disease of congenital insensitivity to pain that comes with birth and consists of not being able to perceive physical pain.

A person who suffers from congenital insensitivity to pain (CIPA) is unable to feel pain and detect extreme temperatures, both hot and cold. It affects only one in 100 million people worldwide and is more common in girls than boys.

At the beginning, the Syndrome was originally described in 1932 by Dearborn as a disease with “pure congenital general analgesia.” 50% of men recognize that women have a greater resistance to pain and endure it more than them.

Similarly, congenital insensitivity to pain with anhidrosis (CIPA) is caused by mutations in the NTRK1 gene, which provides instructions for making a protein that is important for the development and survival of nerve cells (neurons), especially those They carry information about pain, temperature. This can happen in one or more parts of the body.

The cause of loss of sensation may be a complication of diabetes called peripheral neuropathy. As this disease is considered a type of nerve damage, it can be determined after 8 months through a sural nerve biopsy.

Therefore, pain is a signal from the nervous system that something is not right. It is an unpleasant sensation, such as stinging, tingling, stinging, burning, or discomfort. Pain is a very complex subjective phenomenon that has a sensory component and an affective component. Not everyone experiences a painful stimulus in the same way, and this has a lot to do with one’s personality, state of mind, and the type of education we have received.

The five strongest pains that human beings can endure:

  • Cluster headache.
  • Renal colic.
  • Trigeminal neuralgia.
  • Blow to the testicles.
  • Drop.
  • Burns.

The main types of pain are:

  • Acute pain.
  • Chronic pain.
  • Inflammatory pain.
  • Neuropathic pain.
  • Nociceptive pain.

– Neuropathic pain: results from damage or dysfunction of the peripheral or central nervous system, rather than stimulation of pain receptors.

– Diffuse or spread pain: It is pain that is felt in healthy structures, as a result of injury to other structures.

– Somatic pain: it is a well-localized pain and is described as acute. It responds to common analgesics, including anti-inflammatories, opiates, even morphine and its derivatives.

– Visceral pain: is caused by distension of the layers surrounding a visceral organ.

– Mixed pain: it is a type of pain in which the appearance of muscle pain and pain due to nerve damage are combined at the same time and in the same place. It is a common type of pain that affects 6 out of 10 people.

Five methods to control pain with your mind:

  • Healthier alternative.
  • Full attention (mindfulness, in English)
  • Deep breathing.
  • Meditation and visualization.
  • Concentration and positivity.

Finally, according to a study published in the journal Annals of Neurology, the ends of the fingers are considered to be the part of the body most sensitive to pain, as one of the most sensitive points in the body, since they are full of nerve endings that send signals pain directly to the brain.

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https://es.wikipedia.org/wiki/Insensibilidad_cong%C3%A9nita_al_dolor_con_anhidrosis

https://rarediseases.info.nih.gov/espanol/12147/insensibilidad-congenita-al-dolor

https://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S2448-87712017000300042#:~:text=Se%20diagnostica%20a%20los%208%20meses%2C%20mediante%20biopsia%20de%20nervio%20sural.

https://neurologia.com/articulo/2005011

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