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The steroid anti-inflammatory drugs have as an active ingredient cortisone, which are hormones produced by the adrenal cortex or natural corticosteroids and the semisynthetic corticosteroids structural analogues of natural corticosteroids and in particular glucocorticoids.
Especially the most used are synthetic steroids such as dexamethasone or prednisone, among others. Its use is limited or restricted by its side effects or counterproductive, especially those administered oral or parenteral routes as they can produce a drug Cushing Syndrome.
Topical corticosteroids – creams or ointments – are applied to the skin to reduce inflammation such as eczema, dermatitis or psoriasis. Medications such as hydrocortisone, betamethasone and clobetasol are classified as corticosteroids.
A clear example is “Topical Hydrocortisone 1%, 2.5%” which has anti-inflammatory, antipruritic and vasoconstrictive properties. It spreads through cell membranes and forms complexes with specific cytoplasmic receptors.
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